Development of Non-Infringing Synthetic Routes for APIs

Development of Non-Infringing, Novel, Scalable & Green Synthetic Routes for APIs

ARL Labs provides comprehensive development of non-infringing, innovative, and industrially scalable synthetic routes for Active Pharmaceutical Ingredients (APIs), with a strong emphasis on green chemistry, cost efficiency, and freedom-to-operate. Our integrated approach combines advanced synthetic chemistry, IP intelligence, and process engineering to design routes that are patent-safe, environmentally responsible, and commercially viable.

Key Service Offerings:

Novel route scouting with robust patent circumvention and FTO analysis
Design of non-infringing synthetic pathways supported by prior-art evaluation
Green chemistry–driven process development (atom economy, safer reagents, reduced waste)
Cost-effective route optimization with minimized step count and improved yields
Scalable and robust processes suitable for pilot and commercial manufacturing
Solvent, catalyst, and reagent optimization for sustainability and cost reduction
Impurity profiling and control strategies
Technology transfer support documents from lab to scale-up

With proven expertise in API process development, catalysis, medicinal chemistry, and IP strategy, ARL Labs enables pharmaceutical companies to achieve sustainable manufacturing, reduced COGS, and accelerated development timelines without compromising quality or compliance.